Cargando…

Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon Libraries

Staphylococcus aureus is a leading cause of life-threatening infections worldwide. The MIC of an antibiotic against S. aureus, as well as other microbes, is determined by the affinity of the antibiotic for its target in addition to a complex interplay of many other cellular factors. Identifying nont...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajagopal, Mithila, Martin, Melissa J., Santiago, Marina, Lee, Wonsik, Kos, Veronica N., Meredith, Tim, Gilmore, Michael S., Walker, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992970/
https://www.ncbi.nlm.nih.gov/pubmed/27531908
http://dx.doi.org/10.1128/mBio.00950-16