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Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon Libraries
Staphylococcus aureus is a leading cause of life-threatening infections worldwide. The MIC of an antibiotic against S. aureus, as well as other microbes, is determined by the affinity of the antibiotic for its target in addition to a complex interplay of many other cellular factors. Identifying nont...
Autores principales: | Rajagopal, Mithila, Martin, Melissa J., Santiago, Marina, Lee, Wonsik, Kos, Veronica N., Meredith, Tim, Gilmore, Michael S., Walker, Suzanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992970/ https://www.ncbi.nlm.nih.gov/pubmed/27531908 http://dx.doi.org/10.1128/mBio.00950-16 |
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