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HLA-DQ B1*0201 and A1*0102 Alleles Are Not Responsible for Antituberculosis Drug-Induced Hepatotoxicity Risk in Spanish Population

AIMS: To evaluate the role of human leukocyte antigen (HLA) class II DQB1*0201 and DQA1*0102 in the risk of antituberculosis drug (ATD)-induced hepatotoxicity (ATDH) in a cohort of tuberculosis patients of Caucasian origin from Spain. METHODS: Matched case-control study including active tuberculosis...

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Detalles Bibliográficos
Autores principales: Leiro-Fernández, Virginia, Valverde, Diana, Vázquez-Gallardo, Rafael, Constenla-Caramés, Lucía, del Campo-Pérez, Víctor, Fernández-Villar, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992991/
https://www.ncbi.nlm.nih.gov/pubmed/27597944
http://dx.doi.org/10.3389/fmed.2016.00034