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Dual delivery of active antibactericidal agents and bone morphogenetic protein at sustainable high concentrations using biodegradable sheath-core-structured drug-eluting nanofibers

In this study, we developed biodegradable sheath-core-structured drug-eluting nanofibers for sustainable delivery of antibiotics (vancomycin and ceftazidime) and recombinant human bone morphogenetic protein (rhBMP-2) via electrospinning. To prepare the biodegradable sheath-core nanofibers, we first...

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Detalles Bibliográficos
Autores principales: Hsu, Yung-Hen, Lin, Chang-Tun, Yu, Yi-Hsun, Chou, Ying-Chao, Liu, Shih-Jung, Chan, Err-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993267/
https://www.ncbi.nlm.nih.gov/pubmed/27574423
http://dx.doi.org/10.2147/IJN.S107250