Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study

Antibodies of the IgM isotype are often neglected as potential therapeutics in human trials, animal models of human diseases as well as detecting agents in standard laboratory techniques. In contrast, several human IgMs demonstrated proof of efficacy in cancer models and models of CNS disorders incl...

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Detalles Bibliográficos
Autores principales: Watzlawik, Jens O., Kahoud, Robert J., Wootla, Bharath, Painter, Meghan M., Warrington, Arthur E., Carey, William A., Rodriguez, Moses
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993309/
https://www.ncbi.nlm.nih.gov/pubmed/27404858
http://dx.doi.org/10.3791/54139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993309/
https://www.ncbi.nlm.nih.gov/pubmed/27404858
http://dx.doi.org/10.3791/54139

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