Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate

Our understanding on how selective mitochondrial autophagy, or mitophagy, can sustain the archetypal properties of stem cells is incomplete. PTEN-induced putative kinase 1 (PINK1) plays a key role in the maintenance of mitochondrial morphology and function and in the selective degradation of damaged...

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Detalles Bibliográficos
Autores principales: Vazquez-Martin, Alejandro, Van den Haute, Chris, Cufí, Sílvia, Corominas-Faja, Bruna, Cuyàs, Elisabet, Lopez-Bonet, Eugeni, Rodriguez-Gallego, Esther, Fernández-Arroyo, Salvador, Joven, Jorge, Baekelandt, Veerle, Menendez, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993334/
https://www.ncbi.nlm.nih.gov/pubmed/27295498
http://dx.doi.org/10.18632/aging.100976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993334/
https://www.ncbi.nlm.nih.gov/pubmed/27295498
http://dx.doi.org/10.18632/aging.100976

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