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Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate
Our understanding on how selective mitochondrial autophagy, or mitophagy, can sustain the archetypal properties of stem cells is incomplete. PTEN-induced putative kinase 1 (PINK1) plays a key role in the maintenance of mitochondrial morphology and function and in the selective degradation of damaged...
Autores principales: | Vazquez-Martin, Alejandro, Van den Haute, Chris, Cufí, Sílvia, Corominas-Faja, Bruna, Cuyàs, Elisabet, Lopez-Bonet, Eugeni, Rodriguez-Gallego, Esther, Fernández-Arroyo, Salvador, Joven, Jorge, Baekelandt, Veerle, Menendez, Javier A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993334/ https://www.ncbi.nlm.nih.gov/pubmed/27295498 http://dx.doi.org/10.18632/aging.100976 |
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