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Longitudinal decline of leukocyte telomere length in old age and the association with sex and genetic risk

Telomeres are DNA-protein structures at the ends of chromosomes. Leukocyte telomere length (LTL) shortening has been associated with advanced age. However, most studies use cross-sectional data, hence, the aim of our study was to model longitudinal trajectories of LTL attrition across 20 years at ol...

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Detalles Bibliográficos
Autores principales: Berglund, Kari, Reynolds, Chandra A., Ploner, Alexander, Gerritsen, Lotte, Hovatta, Iiris, Pedersen, Nancy L., Hägg, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993338/
https://www.ncbi.nlm.nih.gov/pubmed/27391763
http://dx.doi.org/10.18632/aging.100995