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Cyclin A2 promotes DNA repair in the brain during both development and aging

Various stem cell niches of the brain have differential requirements for Cyclin A2. Cyclin A2 loss results in marked cerebellar dysmorphia, whereas forebrain growth is retarded during early embryonic development yet achieves normal size at birth. To understand the differential requirements of distin...

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Detalles Bibliográficos
Autores principales: Gygli, Patrick E., Chang, Joshua C., Gokozan, Hamza N., Catacutan, Fay P., Schmidt, Theresa A., Kaya, Behiye, Goksel, Mustafa, Baig, Faisal S., Chen, Shannon, Griveau, Amelie, Michowski, Wojciech, Wong, Michael, Palanichamy, Kamalakannan, Sicinski, Piotr, Nelson, Randy J., Czeisler, Catherine, Otero, José J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993346/
https://www.ncbi.nlm.nih.gov/pubmed/27425845
http://dx.doi.org/10.18632/aging.100990