Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

Drug delivery into the brain is impeded by the blood-brain-barrier (BBB) that filters out the vast majority of drugs after systemic administration. In this work, we assessed the transport, uptake and cytotoxicity of promising drug nanocarriers, mesoporous silica nanoparticles (MSNs), in in vitro mod...

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Detalles Bibliográficos
Autores principales: Baghirov, Habib, Karaman, Didem, Viitala, Tapani, Duchanoy, Alain, Lou, Yan-Ru, Mamaeva, Veronika, Pryazhnikov, Evgeny, Khiroug, Leonard, de Lange Davies, Catharina, Sahlgren, Cecilia, Rosenholm, Jessica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993362/
https://www.ncbi.nlm.nih.gov/pubmed/27547955
http://dx.doi.org/10.1371/journal.pone.0160705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993362/
https://www.ncbi.nlm.nih.gov/pubmed/27547955
http://dx.doi.org/10.1371/journal.pone.0160705

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