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KdmB, a Jumonji Histone H3 Demethylase, Regulates Genome-Wide H3K4 Trimethylation and Is Required for Normal Induction of Secondary Metabolism in Aspergillus nidulans

Histone posttranslational modifications (HPTMs) are involved in chromatin-based regulation of fungal secondary metabolite biosynthesis (SMB) in which the corresponding genes—usually physically linked in co-regulated clusters—are silenced under optimal physiological conditions (nutrient-rich) but are...

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Detalles Bibliográficos
Autores principales: Gacek-Matthews, Agnieszka, Berger, Harald, Sasaki, Takahiko, Wittstein, Kathrin, Gruber, Clemens, Lewis, Zachary A., Strauss, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993369/
https://www.ncbi.nlm.nih.gov/pubmed/27548260
http://dx.doi.org/10.1371/journal.pgen.1006222