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KdmB, a Jumonji Histone H3 Demethylase, Regulates Genome-Wide H3K4 Trimethylation and Is Required for Normal Induction of Secondary Metabolism in Aspergillus nidulans
Histone posttranslational modifications (HPTMs) are involved in chromatin-based regulation of fungal secondary metabolite biosynthesis (SMB) in which the corresponding genes—usually physically linked in co-regulated clusters—are silenced under optimal physiological conditions (nutrient-rich) but are...
Autores principales: | Gacek-Matthews, Agnieszka, Berger, Harald, Sasaki, Takahiko, Wittstein, Kathrin, Gruber, Clemens, Lewis, Zachary A., Strauss, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993369/ https://www.ncbi.nlm.nih.gov/pubmed/27548260 http://dx.doi.org/10.1371/journal.pgen.1006222 |
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