MDA‐5 activation by cytoplasmic double‐stranded RNA impairs endothelial function and aggravates atherosclerosis

Recent studies have highlighted the relevance of viral nucleic acid immunorecognition by pattern recognition receptors in atherogenesis. Melanoma differentiation associated gene 5 (MDA‐5) belongs to the intracellular retinoic acid inducible gene‐I like receptors and its activation promotes pro‐infla...

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Detalles Bibliográficos
Autores principales: Asdonk, Tobias, Steinmetz, Martin, Krogmann, Alexander, Ströcker, Christine, Lahrmann, Catharina, Motz, Inga, Paul‐Krahe, Kathrin, Flender, Anna, Schmitz, Theresa, Barchet, Winfried, Hartmann, Gunther, Nickenig, Georg, Zimmer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993381/
https://www.ncbi.nlm.nih.gov/pubmed/27130701
http://dx.doi.org/10.1111/jcmm.12864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993381/
https://www.ncbi.nlm.nih.gov/pubmed/27130701
http://dx.doi.org/10.1111/jcmm.12864

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