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MDA‐5 activation by cytoplasmic double‐stranded RNA impairs endothelial function and aggravates atherosclerosis
Recent studies have highlighted the relevance of viral nucleic acid immunorecognition by pattern recognition receptors in atherogenesis. Melanoma differentiation associated gene 5 (MDA‐5) belongs to the intracellular retinoic acid inducible gene‐I like receptors and its activation promotes pro‐infla...
Autores principales: | Asdonk, Tobias, Steinmetz, Martin, Krogmann, Alexander, Ströcker, Christine, Lahrmann, Catharina, Motz, Inga, Paul‐Krahe, Kathrin, Flender, Anna, Schmitz, Theresa, Barchet, Winfried, Hartmann, Gunther, Nickenig, Georg, Zimmer, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993381/ https://www.ncbi.nlm.nih.gov/pubmed/27130701 http://dx.doi.org/10.1111/jcmm.12864 |
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