Leukocyte Beta-Catenin Expression Is Disturbed in Systemic Lupus Erythematosus

Wnt/β-catenin signaling is relatively understudied in immunity and autoimmunity. β-catenin blocks inflammatory mediators and favors tolerogenic dendritic cell (DC) phenotypes. We show here that leukocytes from lupus-prone mice and SLE patients express diminished β-catenin transcriptional activity, p...

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Detalles Bibliográficos
Autores principales: Orme, Jacob J., Du, Yong, Vanarsa, Kamala, Wu, Tianfu, Satterthwaite, Anne B., Mohan, Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993388/
https://www.ncbi.nlm.nih.gov/pubmed/27548498
http://dx.doi.org/10.1371/journal.pone.0161682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993388/
https://www.ncbi.nlm.nih.gov/pubmed/27548498
http://dx.doi.org/10.1371/journal.pone.0161682

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