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Leukocyte Beta-Catenin Expression Is Disturbed in Systemic Lupus Erythematosus
Wnt/β-catenin signaling is relatively understudied in immunity and autoimmunity. β-catenin blocks inflammatory mediators and favors tolerogenic dendritic cell (DC) phenotypes. We show here that leukocytes from lupus-prone mice and SLE patients express diminished β-catenin transcriptional activity, p...
Autores principales: | Orme, Jacob J., Du, Yong, Vanarsa, Kamala, Wu, Tianfu, Satterthwaite, Anne B., Mohan, Chandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993388/ https://www.ncbi.nlm.nih.gov/pubmed/27548498 http://dx.doi.org/10.1371/journal.pone.0161682 |
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