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The clinicopathological significance of hMLH1 hypermethylation in non-small-cell lung cancer: a meta-analysis and literature review

The hMLH1 gene plays an essential role in DNA repair. Methylation of the hMLH1 gene is common in many types of cancer and can lead to the loss of hMLH1 expression. However, the association and clinicopathological significance between hMLH1 promoter hypermethylation and non-small-cell lung cancer (NS...

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Detalles Bibliográficos
Autores principales: Han, Yi, Shi, Kang, Zhou, Shi-Jie, Yu, Da-Ping, Liu, Zhi-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993409/
https://www.ncbi.nlm.nih.gov/pubmed/27574449
http://dx.doi.org/10.2147/OTT.S106345