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Xenopus Mcm10 is a CDK-substrate required for replication fork stability

During S phase, following activation of the S phase CDKs and the DBF4-dependent kinases (DDK), double hexamers of Mcm2-7 at licensed replication origins are activated to form the core replicative helicase. Mcm10 is one of several proteins that have been implicated from work in yeasts to play a role...

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Detalles Bibliográficos
Autores principales: Chadha, Gaganmeet Singh, Gambus, Agnieszka, Gillespie, Peter J., Blow, J. Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993430/
https://www.ncbi.nlm.nih.gov/pubmed/27327991
http://dx.doi.org/10.1080/15384101.2016.1199305