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West Nile Virus Temperature Sensitivity and Avian Virulence Are Modulated by NS1-2B Polymorphisms

West Nile virus (WNV) replicates in a wide variety of avian species, which serve as reservoir and amplification hosts. WNV strains isolated in North America, such as the prototype strain NY99, elicit a highly pathogenic response in certain avian species, notably American crows (AMCRs; Corvus brachyr...

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Detalles Bibliográficos
Autores principales: Dietrich, Elizabeth A., Langevin, Stanley A., Huang, Claire Y.-H., Maharaj, Payal D., Delorey, Mark J., Bowen, Richard A., Kinney, Richard M., Brault, Aaron C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993437/
https://www.ncbi.nlm.nih.gov/pubmed/27548738
http://dx.doi.org/10.1371/journal.pntd.0004938