Cargando…
14-3-3ζ Mediates Tau Aggregation in Human Neuroblastoma M17 Cells
Microtubule-associated protein tau is the major component of paired helical filaments (PHFs) associated with the neuropathology of Alzheimer’s disease (AD). Tau in the normal brain binds and stabilizes microtubules. Tau isolated from PHFs is hyperphosphorylated, which prevents it from binding to mic...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993442/ https://www.ncbi.nlm.nih.gov/pubmed/27548710 http://dx.doi.org/10.1371/journal.pone.0160635 |