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14-3-3ζ Mediates Tau Aggregation in Human Neuroblastoma M17 Cells

Microtubule-associated protein tau is the major component of paired helical filaments (PHFs) associated with the neuropathology of Alzheimer’s disease (AD). Tau in the normal brain binds and stabilizes microtubules. Tau isolated from PHFs is hyperphosphorylated, which prevents it from binding to mic...

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Detalles Bibliográficos
Autores principales: Li, Tong, Paudel, Hemant K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993442/
https://www.ncbi.nlm.nih.gov/pubmed/27548710
http://dx.doi.org/10.1371/journal.pone.0160635

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