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Crystal Structure of C-Terminal Coiled-Coil Domain of SYCP1 Reveals Non-Canonical Anti-Parallel Dimeric Structure of Transverse Filament at the Synaptonemal Complex

The synaptonemal complex protein 1 (SYCP1) is the main structural element of transverse filaments (TFs) of the synaptonemal complex (SC), which is a meiosis-specific complex structure formed at the synapse of homologue chromosomes to hold them together. The N-terminal domain of SYCP1 is known to be...

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Detalles Bibliográficos
Autores principales: Seo, Eun Kyung, Choi, Jae Young, Jeong, Jae-Hee, Kim, Yeon-Gil, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993509/
https://www.ncbi.nlm.nih.gov/pubmed/27548613
http://dx.doi.org/10.1371/journal.pone.0161379