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Multiple roles for keratin intermediate filaments in the regulation of epithelial barrier function and apico-basal polarity
As multicellular organisms evolved a family of cytoskeletal proteins, the keratins (types I and II) expressed in epithelial cells diversified in more than 20 genes in vertebrates. There is no question that keratin filaments confer mechanical stiffness to cells. However, such a number of genes can ha...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993576/ https://www.ncbi.nlm.nih.gov/pubmed/27583190 http://dx.doi.org/10.1080/21688370.2016.1178368 |