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Multiple roles for keratin intermediate filaments in the regulation of epithelial barrier function and apico-basal polarity

As multicellular organisms evolved a family of cytoskeletal proteins, the keratins (types I and II) expressed in epithelial cells diversified in more than 20 genes in vertebrates. There is no question that keratin filaments confer mechanical stiffness to cells. However, such a number of genes can ha...

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Detalles Bibliográficos
Autores principales: Salas, Pedro J., Forteza, Radia, Mashukova, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993576/
https://www.ncbi.nlm.nih.gov/pubmed/27583190
http://dx.doi.org/10.1080/21688370.2016.1178368