Downregulation of p70S6K Enhances Cell Sensitivity to Rapamycin in Esophageal Squamous Cell Carcinoma

It has been demonstrated that mTOR/p70S6K pathway was abnormally activated in many cancers and rapamycin and its analogs can restrain tumor growth through inhibiting this pathway, but some tumors including esophageal squamous cell carcinoma (ESCC) appear to be insensitive to rapamycin in recent stud...

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Detalles Bibliográficos
Autores principales: Lu, Zhaoming, Peng, Kezheng, Wang, Ning, Liu, Hong-Min, Hou, Guiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993948/
https://www.ncbi.nlm.nih.gov/pubmed/27595116
http://dx.doi.org/10.1155/2016/7828916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993948/
https://www.ncbi.nlm.nih.gov/pubmed/27595116
http://dx.doi.org/10.1155/2016/7828916

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