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Asymmetry in inward- and outward-affinity constant of transport explain unidirectional lysine flux in Saccharomyces cerevisiae

The import of basic amino acids in Saccharomyces cerevisiae has been reported to be unidirectional, which is not typical of how secondary transporters work. Since studies of energy coupling and transport kinetics are complicated in vivo, we purified the major lysine transporter (Lyp1) of yeast and r...

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Detalles Bibliográficos
Autores principales: Bianchi, Frans, Klooster, Joury S. van ‘t, Ruiz, Stephanie J., Luck, Katja, Pols, Tjeerd, Urbatsch, Ina L., Poolman, Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993999/
https://www.ncbi.nlm.nih.gov/pubmed/27550794
http://dx.doi.org/10.1038/srep31443