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Asymmetry in inward- and outward-affinity constant of transport explain unidirectional lysine flux in Saccharomyces cerevisiae
The import of basic amino acids in Saccharomyces cerevisiae has been reported to be unidirectional, which is not typical of how secondary transporters work. Since studies of energy coupling and transport kinetics are complicated in vivo, we purified the major lysine transporter (Lyp1) of yeast and r...
Autores principales: | Bianchi, Frans, Klooster, Joury S. van ‘t, Ruiz, Stephanie J., Luck, Katja, Pols, Tjeerd, Urbatsch, Ina L., Poolman, Bert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993999/ https://www.ncbi.nlm.nih.gov/pubmed/27550794 http://dx.doi.org/10.1038/srep31443 |
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