Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice

Tribbles homolog 2 (Trib2) is a member of Tribbles protein pseudokinases and involves in apoptosis, autoimmunity, cancer, leukemia and erythropoiesis, however, the physiological function of Trib2 in hematopoietic system remains to be elucidated. Here, we report that Trib2 knockout (KO) mice manifest...

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Detalles Bibliográficos
Autores principales: Lin, Kou-Ray, Yang-Yen, Hsin-Fang, Lien, Huang-Wei, Liao, Wei-Hao, Huang, Chang-Jen, Lin, Liang-In, Li, Chung-Leung, Yen, Jeffrey Jong-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994003/
https://www.ncbi.nlm.nih.gov/pubmed/27550848
http://dx.doi.org/10.1038/srep31444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994003/
https://www.ncbi.nlm.nih.gov/pubmed/27550848
http://dx.doi.org/10.1038/srep31444

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