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Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice
Tribbles homolog 2 (Trib2) is a member of Tribbles protein pseudokinases and involves in apoptosis, autoimmunity, cancer, leukemia and erythropoiesis, however, the physiological function of Trib2 in hematopoietic system remains to be elucidated. Here, we report that Trib2 knockout (KO) mice manifest...
Autores principales: | Lin, Kou-Ray, Yang-Yen, Hsin-Fang, Lien, Huang-Wei, Liao, Wei-Hao, Huang, Chang-Jen, Lin, Liang-In, Li, Chung-Leung, Yen, Jeffrey Jong-Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994003/ https://www.ncbi.nlm.nih.gov/pubmed/27550848 http://dx.doi.org/10.1038/srep31444 |
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