Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC

Non-small-cell lung cancer is the leading cause of cancer death worldwide and is comprised of several histological subtypes, the two most common being adenocarcinoma (AC) and squamous cell carcinoma (SCC). Targeted therapies have successfully improved response rates in patients with AC tumors. Howev...

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Detalles Bibliográficos
Autores principales: Taylor, M A, Wappett, M, Delpuech, O, Brown, H, Chresta, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994018/
https://www.ncbi.nlm.nih.gov/pubmed/26776158
http://dx.doi.org/10.1038/onc.2015.499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994018/
https://www.ncbi.nlm.nih.gov/pubmed/26776158
http://dx.doi.org/10.1038/onc.2015.499

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