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Disease-Homologous Mutation in the Cation Diffusion Facilitator Protein MamM Causes Single-Domain Structural Loss and Signifies Its Importance

Cation diffusion facilitators (CDF) are highly conserved, metal ion efflux transporters that maintain divalent transition metal cation homeostasis. Most CDF proteins contain two domains, the cation transporting transmembrane domain and the regulatory cytoplasmic C-terminal domain (CTD). MamM is a ma...

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Detalles Bibliográficos
Autores principales: Barber-Zucker, Shiran, Uebe, René, Davidov, Geula, Navon, Yotam, Sherf, Dror, Chill, Jordan H., Kass, Itamar, Bitton, Ronit, Schüler, Dirk, Zarivach, Raz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994047/
https://www.ncbi.nlm.nih.gov/pubmed/27550551
http://dx.doi.org/10.1038/srep31933