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Disease-Homologous Mutation in the Cation Diffusion Facilitator Protein MamM Causes Single-Domain Structural Loss and Signifies Its Importance
Cation diffusion facilitators (CDF) are highly conserved, metal ion efflux transporters that maintain divalent transition metal cation homeostasis. Most CDF proteins contain two domains, the cation transporting transmembrane domain and the regulatory cytoplasmic C-terminal domain (CTD). MamM is a ma...
Autores principales: | Barber-Zucker, Shiran, Uebe, René, Davidov, Geula, Navon, Yotam, Sherf, Dror, Chill, Jordan H., Kass, Itamar, Bitton, Ronit, Schüler, Dirk, Zarivach, Raz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994047/ https://www.ncbi.nlm.nih.gov/pubmed/27550551 http://dx.doi.org/10.1038/srep31933 |
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