Thyrotropin Receptor Epitope and Human Leukocyte Antigen in Graves’ Disease

Graves’ disease (GD) is an organ-specific autoimmune disease, and thyrotropin (TSH) receptor (TSHR) is a major autoantigen in this condition. Since the extracellular domain of human TSHR (TSHR-ECD) is shed into the circulation, TSHR-ECD is a preferentially immunogenic portion of TSHR. Both genetic f...

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Detalles Bibliográficos
Autores principales: Inaba, Hidefumi, De Groot, Leslie J., Akamizu, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994058/
https://www.ncbi.nlm.nih.gov/pubmed/27602020
http://dx.doi.org/10.3389/fendo.2016.00120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994058/
https://www.ncbi.nlm.nih.gov/pubmed/27602020
http://dx.doi.org/10.3389/fendo.2016.00120

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