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Modulation of IL-6 induced RANKL expression in arthritic synovium by a transcription factor SOX5

Receptor activator of nuclear factor κB ligand (RANKL) is critically involved in bone erosion of rheumatoid arthritis (RA). We previously reported association between younger age at onset of RA and a RANKL promoter SNP that conferred an elevated promoter activity via binding to a transcription facto...

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Detalles Bibliográficos
Autores principales: Feng, Xiaoke, Shi, Yumeng, Xu, Lingxiao, Peng, Qiuyue, Wang, Fang, Wang, Xiaoxi, Sun, Wei, Lu, Yan, Tsao, Betty P., Zhang, Miaojia, Tan, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994074/
https://www.ncbi.nlm.nih.gov/pubmed/27550416
http://dx.doi.org/10.1038/srep32001