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Central chronic apelin infusion decreases energy expenditure and thermogenesis in mice

Apelin is a bioactive peptide involved in the control of energy metabolism. In the hypothalamus, chronic exposure to high levels of apelin is associated with an increase in hepatic glucose production, and then contributes to the onset of type 2 diabetes. However, the molecular mechanisms behind dele...

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Detalles Bibliográficos
Autores principales: Drougard, Anne, Fournel, Audren, Marlin, Alysson, Meunier, Etienne, Abot, Anne, Bautzova, Tereza, Duparc, Thibaut, Louche, Katie, Batut, Aurelie, Lucas, Alexandre, Le-Gonidec, Sophie, Lesage, Jean, Fioramonti, Xavier, Moro, Cedric, Valet, Philippe, Cani, Patrice D., Knauf, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994119/
https://www.ncbi.nlm.nih.gov/pubmed/27549402
http://dx.doi.org/10.1038/srep31849