Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C

BACKGROUND: Serine–arginine rich splicing factor 2 (SRSF2) is a protein known for its role in RNA splicing and genome stability. It has been recently discovered that SRSF2, along with other splicing regulators, is frequently mutated in patients with myelodysplastic syndrome (MDS). The most common MD...

Descripción completa

Detalles Bibliográficos
Autores principales: Skrdlant, Lindsey, Stark, Jeremy M., Lin, Ren-Jang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994158/
https://www.ncbi.nlm.nih.gov/pubmed/27552991
http://dx.doi.org/10.1186/s12867-016-0071-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994158/
https://www.ncbi.nlm.nih.gov/pubmed/27552991
http://dx.doi.org/10.1186/s12867-016-0071-y

Ejemplares similares