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The effects of prenatal metformin on obesogenic diet-induced alterations in maternal and fetal fatty acid metabolism

BACKGROUND: Maternal obesity may program the fetus and increase the susceptibility of the offspring to adult diseases. Metformin crosses the placenta and has been associated with decreased inflammation and reversal of fatty liver in obese leptin-deficient mice. We investigated the effects of metform...

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Detalles Bibliográficos
Autores principales: Harris, Kemoy, Desai, Neeraj, Gupta, Madhu, Xue, Xiangying, Chatterjee, Prodyot K., Rochelson, Burton, Metz, Christine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994240/
https://www.ncbi.nlm.nih.gov/pubmed/27555877
http://dx.doi.org/10.1186/s12986-016-0115-9