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The effects of prenatal metformin on obesogenic diet-induced alterations in maternal and fetal fatty acid metabolism
BACKGROUND: Maternal obesity may program the fetus and increase the susceptibility of the offspring to adult diseases. Metformin crosses the placenta and has been associated with decreased inflammation and reversal of fatty liver in obese leptin-deficient mice. We investigated the effects of metform...
Autores principales: | Harris, Kemoy, Desai, Neeraj, Gupta, Madhu, Xue, Xiangying, Chatterjee, Prodyot K., Rochelson, Burton, Metz, Christine N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994240/ https://www.ncbi.nlm.nih.gov/pubmed/27555877 http://dx.doi.org/10.1186/s12986-016-0115-9 |
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