Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a disease with a strong neuroinflammatory component sustained by activated microglia contributing to motoneuron death. However, how to successfully balance neuroprotective versus neurotoxic actions by the use of antinflammatory agents is still under...

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Detalles Bibliográficos
Autores principales: Apolloni, Savina, Fabbrizio, Paola, Amadio, Susanna, Volonté, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994328/
https://www.ncbi.nlm.nih.gov/pubmed/27549088
http://dx.doi.org/10.1186/s12974-016-0658-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994328/
https://www.ncbi.nlm.nih.gov/pubmed/27549088
http://dx.doi.org/10.1186/s12974-016-0658-8

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