Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity

BACKGROUND: Histone deacetylase inhibitors (HDACi) exert multiple cytotoxic actions on cancer cells. Currently, different synthetic HDACi are in clinical use or clinical trials; nevertheless, since both pro-invasive and anti-invasive activities have been described, there is some controversy about th...

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Detalles Bibliográficos
Autores principales: Díaz-Núñez, María, Díez-Torre, Alejandro, De Wever, Olivier, Andrade, Ricardo, Arluzea, Jon, Silió, Margarita, Aréchaga, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994393/
https://www.ncbi.nlm.nih.gov/pubmed/27549189
http://dx.doi.org/10.1186/s12885-016-2693-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994393/
https://www.ncbi.nlm.nih.gov/pubmed/27549189
http://dx.doi.org/10.1186/s12885-016-2693-3

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