Cargando…

Genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with Alzheimer's disease

Genistein is effective against amyloid-β toxicity, but the underlying mechanisms are unclear. We hypothesized that genistein may protect neurons by inhibiting the mitochondrial apoptotic pathway, and thereby play a role in the prevention of Alzheimer’s disease. A rat model of Alzheimer’s disease was...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yan, Cai, Biao, Shao, Jing, Wang, Ting-ting, Cai, Run-ze, Ma, Chang-ju, Han, Tao, Du, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994461/
https://www.ncbi.nlm.nih.gov/pubmed/27630702
http://dx.doi.org/10.4103/1673-5374.187056