Functional and structural characterization of axonal opioid receptors as targets for analgesia

BACKGROUND: Opioids are the gold standard for the treatment of acute pain despite serious side effects in the central and enteric nervous system. µ-opioid receptors (MOPs) are expressed and functional at the terminals of sensory axons, when activated by exogenous or endogenous ligands. However, the...

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Detalles Bibliográficos
Autores principales: Mambretti, Egle M, Kistner, Katrin, Mayer, Stefanie, Massotte, Dominique, Kieffer, Brigitte L, Hoffmann, Carsten, Reeh, Peter W, Brack, Alexander, Asan, Esther, Rittner, Heike L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994859/
https://www.ncbi.nlm.nih.gov/pubmed/27030709
http://dx.doi.org/10.1177/1744806916628734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994859/
https://www.ncbi.nlm.nih.gov/pubmed/27030709
http://dx.doi.org/10.1177/1744806916628734

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