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Functional and structural characterization of axonal opioid receptors as targets for analgesia

BACKGROUND: Opioids are the gold standard for the treatment of acute pain despite serious side effects in the central and enteric nervous system. µ-opioid receptors (MOPs) are expressed and functional at the terminals of sensory axons, when activated by exogenous or endogenous ligands. However, the...

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Detalles Bibliográficos
Autores principales:	Mambretti, Egle M, Kistner, Katrin, Mayer, Stefanie, Massotte, Dominique, Kieffer, Brigitte L, Hoffmann, Carsten, Reeh, Peter W, Brack, Alexander, Asan, Esther, Rittner, Heike L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994859/ https://www.ncbi.nlm.nih.gov/pubmed/27030709 http://dx.doi.org/10.1177/1744806916628734

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