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Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks

Cell cycle (CC) and TP53 regulatory networks are frequently deregulated in cancer. While numerous genome-wide studies of TP53 and CC-regulated genes have been performed, significant variation between studies has made it difficult to assess regulation of any given gene of interest. To overcome the li...

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Detalles Bibliográficos
Autores principales: Fischer, Martin, Grossmann, Patrick, Padi, Megha, DeCaprio, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994865/
https://www.ncbi.nlm.nih.gov/pubmed/27280975
http://dx.doi.org/10.1093/nar/gkw523