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The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation

Ischemic heart disease is a major cause of death and morbidity and the search for novel therapeutic targets is still required. We have previously shown that the enzyme arachidonate 15 lipoxygenase (ALOX15), which catalyzes the conversion of arachidonic acid to 15-hydroxy eicosatetraenoic acid (15-HE...

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Detalles Bibliográficos
Autores principales: Lundqvist, Annika, Sandstedt, Mikael, Sandstedt, Joakim, Wickelgren, Ruth, Hansson, Göran I., Jeppsson, Anders, Hultén, Lillemor Mattsson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994938/
https://www.ncbi.nlm.nih.gov/pubmed/27552229
http://dx.doi.org/10.1371/journal.pone.0161629