Cargando…
The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation
Ischemic heart disease is a major cause of death and morbidity and the search for novel therapeutic targets is still required. We have previously shown that the enzyme arachidonate 15 lipoxygenase (ALOX15), which catalyzes the conversion of arachidonic acid to 15-hydroxy eicosatetraenoic acid (15-HE...
Autores principales: | Lundqvist, Annika, Sandstedt, Mikael, Sandstedt, Joakim, Wickelgren, Ruth, Hansson, Göran I., Jeppsson, Anders, Hultén, Lillemor Mattsson |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994938/ https://www.ncbi.nlm.nih.gov/pubmed/27552229 http://dx.doi.org/10.1371/journal.pone.0161629 |
Ejemplares similares
-
Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner
por: Sandstedt, Mikael, et al.
Publicado: (2018) -
Arachidonate 15-Lipoxygenase Enzyme Products Increase Platelet Aggregation and Thrombin Generation
por: Vijil, Carolina, et al.
Publicado: (2014) -
Arachidonate 15-Lipoxygenase Type B Knockdown Leads to Reduced Lipid Accumulation and Inflammation in Atherosclerosis
por: Magnusson, Lisa U., et al.
Publicado: (2012) -
Metagenomic sequencing of human cardiac tissue reveals Microbial RNA which correlates with Toll-like receptor-associated inflammation in patients with heart disease
por: Sandstedt, Joakim, et al.
Publicado: (2023) -
Wide QRS‐T angles are associated with markers of increased inflammatory activity independently of hypertension and diabetes
por: Sandstedt, Mikael, et al.
Publicado: (2020)