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Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium

Melanosomes of retinal pigment epithelium (RPE) have many vision supporting functions. Melanosome research would benefit from a method to isolate pure and characterized melanosomes. Sucrose gradient centrifugation is the most commonly used method for isolation of RPE melanosomes, but the isolated pr...

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Detalles Bibliográficos
Autores principales: Pelkonen, Laura, Reinisalo, Mika, Morin-Picardat, Emmanuelle, Kidron, Heidi, Urtti, Arto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994940/
https://www.ncbi.nlm.nih.gov/pubmed/27551967
http://dx.doi.org/10.1371/journal.pone.0160352