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Atopy and Inhaled Corticosteroid Use Associate with Fewer IL-17(+) Cells in Asthmatic Airways

BACKGROUND: Interleukin (IL)-17 plays a critical role in numerous immune and inflammatory responses and was recently suggested to contribute to the pathogenesis of nonatopic (non-eosinophil/neutrophil-dominant) asthma. We aimed to compare expression of IL-17 in bronchial airways between atopic and n...

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Detalles Bibliográficos
Autores principales: Fattahi, Fatemeh, Brandsma, Corry-Anke, Lodewijk, Monique, Reinders-Luinge, Marjan, Postma, Dirkje S., Timens, Wim, Hylkema, Machteld N., ten Hacken, Nick H. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994949/
https://www.ncbi.nlm.nih.gov/pubmed/27552197
http://dx.doi.org/10.1371/journal.pone.0161433