Large-Scale Recombinant Expression and Purification of Human Tyrosinase Suitable for Structural Studies

Human tyrosinase (TYR) is a glycoprotein that initiates the first two reactions in the melanin biosynthesis pathway. Mutations in its encoding gene cause Oculocutaneous Albinism type I (OCA1), the most severe form of albinism, which is a group of autosomal recessive disorders characterized by reduce...

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Detalles Bibliográficos
Autores principales: Lai, Xuelei, Soler-Lopez, Montserrat, Wichers, Harry J., Dijkstra, Bauke W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994950/
https://www.ncbi.nlm.nih.gov/pubmed/27551823
http://dx.doi.org/10.1371/journal.pone.0161697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994950/
https://www.ncbi.nlm.nih.gov/pubmed/27551823
http://dx.doi.org/10.1371/journal.pone.0161697

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