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Large-Scale Recombinant Expression and Purification of Human Tyrosinase Suitable for Structural Studies
Human tyrosinase (TYR) is a glycoprotein that initiates the first two reactions in the melanin biosynthesis pathway. Mutations in its encoding gene cause Oculocutaneous Albinism type I (OCA1), the most severe form of albinism, which is a group of autosomal recessive disorders characterized by reduce...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994950/ https://www.ncbi.nlm.nih.gov/pubmed/27551823 http://dx.doi.org/10.1371/journal.pone.0161697 |