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Discovery of a Family of Genomic Sequences Which Interact Specifically with the c-MYC Promoter to Regulate c-MYC Expression

G-quadruplex forming sequences are particularly enriched in the promoter regions of eukaryotic genes, especially of oncogenes. One of the most well studied G-quadruplex forming sequences is located in the nuclease hypersensitive element (NHE) III(1) of the c-MYC promoter region. The oncoprotein c-MY...

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Detalles Bibliográficos
Autores principales: Rezzoug, Francine, Thomas, Shelia D., Rouchka, Eric C., Miller, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995011/
https://www.ncbi.nlm.nih.gov/pubmed/27551915
http://dx.doi.org/10.1371/journal.pone.0161588